Very Early Nimodipine Use in Stroke (VENUS)

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Very Early Nimodipine Use in Stroke (VENUS)

Backgound and Purpose—The Very Early Nimodipine Use in Stroke (VENUS) trial was designed to test the hypothesis that early treatment with nimodipine has a positive effect on survival and functional outcome after stroke. This was suggested in a previous meta-analysis on the use of nimodipine in stroke. However, in a recent Cochrane review we were unable to reproduce these positive results. This ...

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Very Early Nimodipine Use in Stroke (VENUS): a randomized, double-blind, placebo-controlled trial.

BACKGROUND AND PURPOSE The Very Early Nimodipine Use in Stroke (VENUS) trial was designed to test the hypothesis that early treatment with nimodipine has a positive effect on survival and functional outcome after stroke. This was suggested in a previous meta-analysis on the use of nimodipine in stroke. However, in a recent Cochrane review we were unable to reproduce these positive results. This...

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AMOBES (Active Mobility Very Early After Stroke)

In the early stage after stroke, within the first 2 weeks, physical therapy (PT) has 2 main goals: prevent immobilityrelated events and stimulate motor control recovery. However, the amount of PT to provide and the time after stroke for provision remain unclear. The organization of care in multidisciplinary stroke units has reduced the risk of death and dependency after stroke, with early mobil...

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Very early versus delayed mobilisation after stroke.

BACKGROUND Very early mobilisation is performed in some stroke units and recommended in acute stroke clinical guidelines. It is unclear whether very early mobilisation independently improves outcome after stroke. OBJECTIVES To determine the benefits and harms of very early mobilisation (commenced within 48 hours of stroke) compared with conventional care. SEARCH STRATEGY We searched the Coc...

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Nimodipine and perfusion changes after stroke.

BACKGROUND AND PURPOSE Meta-analysis of previous trials of oral nimodipine in acute stroke has suggested a benefit when commenced within 12 hours of onset. We sought to study the effect of oral nimodipine on reperfusion after acute stroke and the relation between reperfusion and outcome. METHODS Fifty patients with acute middle cerebral artery territory cortical infarction were blindly random...

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ژورنال

عنوان ژورنال: Stroke

سال: 2001

ISSN: 0039-2499,1524-4628

DOI: 10.1161/01.str.32.2.461